International Journal of Drug Discovery and Medical Research

BONE MARROW TREPINE BIOPSY: STILL AN IMPORTANT DIAGNOSTIC TOOL IN THE 21ST CENTURY

2023-06-01T04:44:30-04:00

Trepine biopsy is an indispensable diagnostic tool in the 21st century, and despite its long origins, its value remains innovative
in developing countries. The outcome of a bone marrow biopsy report depends on many factors, including detailed patient
clinical information, cross-departmental affiliations, working knowledge, and the technical capabilities of staff. Molecular
studies of biopsies are needed to increase diagnostic accuracy and personalize treatment. We have reviewed articles on
trephine biopsy and its challenges to re-emphasize that trepine biopsy are an essential diagnostic tool in our time.

PERIOPERATIVE PSYCHIATRIC DISORDERS

2023-06-01T05:04:21-04:00

Background: Surgery is a very stressful situation for humans, resulting in various psychiatric problems. Fear of the operation
process, fear of the unknown, death anxiety along with changes in primary personal, family and professional roles, cause the
manifestation of problems from the mental realm. The effects of psychiatric disorders can have a profound effect on both the
mental and physical health of the patient.
Aim: The aim of this study is to present psychiatric disorders during the Perioperative period.
Material and method: The method used to write this study is the literature review. The writing was done by studying books,
scientific articles and internet search.
Results: Psychiatric problems such as anxiety, depression, delirium at their onset, affect the preoperative and postoperative
condition of the patient.
Conclusions: The evaluation of psychiatric disorders experienced by patients should be an integral part of perioperative care.
Early diagnosis and early treatment are associated with the avoidance of chronicity and serious complications

THE HEALTH SYSTEM IN SUDAN IS CHARACTERISED BY HEAVY RELIANCE ON CHARGING USERS AT THE POINT OF ACCESS

2023-06-01T05:14:36-04:00

The strategy of price liberalisation and privatisation had been implemented in Sudan over the last
decade, and has had a positive result on government deficit. The investment law approved recently has
good statements and rules on the above strategy in particular to pharmacy regulations. Under the
pressure of the new privatisation policy, the government introduced radical changes in the pharmacy
regulations. To improve the effectiveness of the public pharmacy, resources should be switched towards
areas of need, reducing inequalities and promoting better health conditions. Medicines are financed
either through cost sharing or full private. The role of the private services is significant. A review of
reform of financing medicines in Sudan is given in this article. Also, it highlights the current drug supply
system in the public sector, which is currently responsibility of the Central Medical Supplies Public
Corporation (CMS). In Sudan, the researchers did not identify any rigorous evaluations or quantitative
studies about the impact of drug regulations on the quality of medicines and how to protect public health
against counterfeit or low quality medicines, although it is practically possible. However, the regulations
must be continually evaluated to ensure the public health is protected against by marketing high quality
medicines rather than commercial interests, and the drug companies are held accountable for their
conducts.

SOCIAL SUPPORT AND PROMOTION OF THE WELLBEING IN WOMEN OF HALF AGE WITH CANCER OF NON-METASTATIC SUCKLE

2023-06-01T05:45:39-04:00

Objective: to propose a program of social support for the promotion of the well-being in women of half age with cancer of not
suckles metastatic residents in Santa Clara. The investigation embraced one period from January 2020 to January 2022 of the
Province Hospital “Celestino Hernandez Robau". Materials and methods: for sampling intentional non probabilistic composed
by 23 women of half age with cancer of suckles non metastatic. It gathers it of the data was carried out through the empiric
method the questionnaire and for the analysis of the data the statistical calculation was used. Results: it allowed the
introduction of improv ements in their design toward women of half age with cancer of suckles non metastatic. Conclusions: it
contributed to the establishment of a logical and coherent articulation among the specific objectives and the projects
psychosocial that compose the program.

EXPLORATORY MODEL OF INTENTION TO VOTE IN THE COVID-19 ERA

2023-06-01T05:58:32-04:00

Organizational lucidity and social responsibility corporate are two processes that explain the propensity of employees to
support their companies and politicians linked to it in an electoral contest, but when these voters perceive that rather the
government authorities limit the ecological initiatives of the companies, then their preferences, intentions and suffrages they
opt for alternative options to those of the government candidate in turn. Therefore, the objective of this paper has been to
establish the reliability and validity of an instrument that measures the expectations and intentions of voting in favor of
candidates that respect the environment to be able to contrast a model for the integral study of the phenomenon in different
contexts and samples. From a structural model It was observed that the expected risks and benefits directly predict and
indirectly through the expectations of consensus and dissent to the intention to vote in favor of a candidate of the current
administration, or to an alternative candidate. Research lines are recommended concerning the provisions of the voters with
respect to local environmental norms and values.

COMMUNITY HEALTH ISSUES AND USE OF ALTERNATIVE CHEMICAL FORMULA RELATED AGENTS AS THERAPY

2023-06-01T06:03:56-04:00

The most widely recognized of the metabolic risk factors are atherogenic dyslipidemia, elevated blood pressure, and elevated
plasma glucose. Individuals with these characteristics commonly manifest a prothrombotic state and a pro -inflammatory state
as well. Atherogenic dyslipidemia consists of an aggregation of lipoprotein abnormalities including elev ated serum trigl yceri de
and apolipoprotein B (apoB), increased small LDL particles, and a reduced level of HDL cholesterol (HDL-C). The metabolic
syndrome is often referred to as if it were a discrete entity with a single cause. Available data suggest that it truly is a
syndrome, ie, a grouping of ASCVD risk factors, but one that probably has more than one cause. Regardless of cause, the
syndrome identifies individuals at an elevated risk for ASCVD. The magnitude of the increased risk can v ary according to
which components of the syndrome are present plus the other, non-metabolic syndrome risk factors in a particular person.
Design and Place of conduction: The research work was single blind placebo-controlled, conducted at Jinnah Hospital, Lahore
Research time: It was conducted from April 2021 to October 2021. Number of patients and their Age: Seventy five already
diagnosed primary and secondary hyperlipidemic patients were selected with age range from 17 to 65 years. Exclusion
criteria: Diabetes mellitus, cigarette smoking/alcohol addictive patients, peptic ulcer disease, hypothyroidism, kidney
dysfunction, any heart disease and liver disease. All patients were divided in three groups (group-I, group-II, group-III), 25 in
each group. Proforma for patients: Their baseline lipid profile data were taken and filed in specifically designed Performa, at
start of taking medicine. Patients group division: Twenty five patients of group-I were advised to take 10 grams of Flaxseeds in
three divided doses after meal. Twenty five patients of group-II were advised to take Ajwain seeds 10 grams in three divided
doses after each meal for two months. Twenty five patients of group-III were provided placebo capsul es, (containing grinded
rice), taking one capsule after each meal. All participants were advised to take these medicines for eight weeks. Follow-up
period: All participants were called fortnightly for their query and follow up. Their LDL-cholesterol and HDL-cholesterol was
determined at the hospital laboratory. Resul ts: In two months therapy by Flaxseeds decreased LDL-cholesterol from
195.11±2.11 mg/dl to 190.22±3.11 mg/dl, which is significant statistically. HDL was increased from 34.53±1.65 mg/dl to
38.97±2.29 mg/d, which is also significant change. In two months therapy by AJWAIN, LDL-c reduced from 201.51±2.62 mg/dl
to 197.11±2.66 mg/dl, which is significant statistically. HDL-cholesterol increased by Ajwain from 36.97±3.32 mg/dl to
37.45±1.87 mg/dl, which is insignificant statistically