HEMOGLOBINOPATHIES IN VADODARA: A HOSPITAL-BASED STUDY

Abstract

The inherited disorders of hemoglobin are responsible for an extremely complex series of clinical phenotypes. Sickle cell
anemia and thalassemia can cause chronic ill-health and life-threatening situations. Present study was carried out at
pipaiya, Vadodara, Gujarat state. The practice of consanguineous marriages is an accepted sociocultural Phenomenon in
this region. This study was hospital-based and the pediatric cases of hemoglobinopathies were identified based on clinical
data, family history, red blood cell indices and hemoglobin in electrophoresis. Sickle cell disorder has remained a
neglected field of research in our country. The present study was started in rural population of Gujarat to find out the
magnitude of sickle cell disorders. 46 subjects were studied. . Through this study, we created awareness among people
about the disorders. The villagers were explained about its’ hereditary nature and that no curative treatment is available,
although it can be prevented through marriage counseling. It is necessary to continue with such activities since
prevention appears to be the only solution in present circumstances.
Purpose & priorities goal: No Child birth with Sickle Disease by 2020, Prevention of death from Sickle Cell Crisis, To
improve health status and quality of life of Sickle Cell Anemia patients. Hemoglobinopathies pose economical and
psychosocial burden Extensive screening for hemoglobinopathies is very much essential, Socio-cultural aspects of a
region need to be explored to evaluate their Interaction with genetic factors.