PHARMACOTHERAPY OF NEPHROPATHY: A REVIEW

Abstract

Nephropathy develops progressively in diabetic patients such that it becomes a major contributor risk factor for death from
cardiovascular complications. It is a common and disabilitating complication of diabetes mellitus with no effective therapy. Acute
uric acid nephropathy (AUAN, also acute urate nephropathy) is a rapidly worsening (decreasing) kidney function (renal
insufficiency) that is caused by high levels of uric acid in the urine (hyperuricosuria). Chronic Kidney Disease: Chronic renal failure
(CRF) is the gradual reduction of kidney function that may lead to permanent kidney failure, or end-stage. Diabetic nephropathy
(nephropatia diabetica), also known as Kimmelstiel-Wilson syndrome, or nodular diabetic glomerulosclerosis. and intercapillary
glomerulonephritis, is a progressive kidney disease caused by angiopathy of capillaries in the kidney glomeruli. It is characterized
by nephrotic syndrome and diffuse glomerulosclerosis. It is due to longstanding diabetes mellitus, and is a prime indication for
dialysis in many Western countries. Exploration of traditional medicine is a mysteriously interesting yet, scientifically significant
and economically important task of ethno botanists. The people of India are well acquainted with a large number of indigenous
medicinal plants than the natives of any other countries. Herbs are the principal form of medicine in India and they are becoming
popular throughout the world.